ICE Logo Innovative Cryo Enterprises LLC

                                                     Your resource for cryopreservation of reproductive cells and tissues

 office (973) 632-8635 

About I.C.E.

I.C.E. is a research and consulting company that specalizes in the cryopreservation of gametes and embryos.  Our expertise covers human reproduction, as well as domestic and nondomestic mammalian species.


I.C.E. endeavors to provide the best cryopreservation systems available. 

We have a long lasting commitment to assist fertility clinics and other institutions in achieving their highest rate of success in thier cryo-storage program; today and for years to come.  We strive to further improve our already successful I.C.E. vitrification system for oocytes, embryos, and blastocysts.  Our goal is to help one clinic at a time by offering a superior product at a reasonable price, along with dedicated service. 


Our team of experts can help you!  We have organized a group of scientists, embryologists, and reproductive endocrinologists to help you with any problem or question you may have about your cryopreservation program.  The success of a vitrification program is dependant upon much more than just survival after warming!  Our experts in laboratory set-up, embryo culture, cryopreservation, embryo transfer, and patient stimulation are here to help you with whatever question you may have.  Check out their biographies below.  Please contact us with any questions you may have and we will try to help you out. 



James Stachecki, Ph.D. founder of I.C.E. LLC has worked in the cryopreservation field for over 20 years.  He pioneered the use of choline chloride as a substitute for sodium chloride for slow-cooling oocytes.  In 1998 he received the general prize paper award at the ASRM annual meeting for his work vitrifying human oocytes.  A year later was granted a US patent for his choline-based freezing medium.  Almost 11 years ago he developed a vitrification system for blastocysts that was DMSO-free and used conventional cryo-straws.  This large-volume system was markedly different that the DMSO/EG micro-volume system being developed around the same time.  A similar large-volume system was later developed for oocytes and cleavage-stage embryos.  Today, these systems have grown in popularity because of their simplicity, cost effectiveness, and their success (ie. clinical pregnancy rate).  Originally the system was called "S3" or S3.   This stood for "Simple, Safe, and Successful".  We have modified and improved the formulation and protocols to such a degree that we feel a new name is appropriate.  Although the basic concepts are the same, overall, it is a much better system than the one published just 5 years ago.  The system is now called  "ICE Vitrification".  We are always trying to improve this already successful system, in hopes of increasing survival and pregnancy rates so that all clinics using the system will achieve results similar to their fresh/nonfrozen embryo transfer rates.  Currently we are working at a better system for cryopreserving sperm and ovarian tissue. 


I.C.E. Team Members / Scientific Advisory Board

Sharon Anderson, Ph.D. H.C.L.D. -- Lab Director, Senior Embryologist

Michael DeMattina, M.D. -- Reproductive Endocrinoligist

Andrea DeVenuta, M.S. -- Senior Embryologist

Michael Lee, Ph.D. H.C.L.D. -- Lab Director, Senior Embryologist

Mitchell Schiewe, Ph.D. H.C.L.D. -- Lab Director, Senior Embryologist

Amy Sparks, Ph.D. H.C.L.D. --  Lab Director, Senior Embryologist


For More Information

  • Call or email us for any of your questions regarding vitrification or cryopreservation of cells or tissues.  (973) 632-8635

  • Visit the "News" and "Help Desk" sections on this website for more information about vitrification.

  • Over 40 clinics throughout the world are currently using the ICE vitrification system.  Find out how this easy to use system can help your patients.  Please visit our products page for more details.

James Stachecki Ph.D.

James J. Stachecki, Ph.D.

Founder and president